IMU-838

IMU-838 – Target DHODH

IMU-838 is an orally available, next-generation, small molecule inhibitor of “dihydroorotate dehydrogenase” (DHODH) which plays a key role in the metabolism of activated T and B cells while leaving other immune cells largely unaffected.

IMU-838 diagramm

Modified after Haghikia et al. Nature Reviews Neurology 10, 183–184 (2014)